| 14th Street Community Center | 1222 14th Street Portsmouth Oh 45662 | | 31-4409973 |
| 7 Nations Celtic Club of Southern Ohio | 424 Chillicothe St, Portsmouth, OH 45662, Usa | | 20-5907125 |
| A Future Without Poverty | 5365 Old Us Hwy 68, Georgetown, OH 45121, Usa | | 20-3577722 |
| A.L.P.H.A. Pets & Food Bank | 7048 Dixon Pike Maysville, KY 41056 | | 45-4660276 |
| Adams County Arts Council | 117 E North St, West Union, OH 45693, Usa | | 31-1409478 |
| Adams County Children Services | 300 North Wilson Drive West Union, Ohio 45693 | | 83-1249546 |
| Adams County OSU Extension | 215 N Cross St Rm.104, West Union, OH 45693, Usa | | 80-0535740 |
| Adams County Regional Medical Center | 230 Medical Center Dr, Seaman, OH 45679, Usa | | 81-2817266 |
| Adams County Shelter for the Homeless (ACSH) | 11483 State Route 41 West Union, OH 45693 | | 31-1408111 |
| Adams County Suicide Prevention Coalition | 78 Chrisdon Ln, West Union, OH 45693-8809 | | 81-3060380 |
| Ascend Counseling and Recovery Services | 729 6th Street Portsmouth , OH 45662 | | 45-2710648 |
| Brown County Humane Society | 100 Veterans Blvd, Georgetown, OH 45121, Usa | | 31-0895108 |
| Butler Springs Christian Camp | 3701 State Rte 41, Hillsboro, OH 45133, Usa | | 31-0581700 |
| CASA Program for Bracken, Fleming, and Mason Counties | 100 W 3rd St, Maysville, KY 41056, Usa | | 61-1322742 |
| Chatfield College - St. Martin Campus | 20918 Oh-251, Fayetteville, OH 45118, Usa | | 31-0840764 |
| Cherry Ridge Therapeutic Learning Programs | 4120 Vinegar Hill Rd, Georgetown, Ohio 45121 | | 20-4481259 |
| Christians Beyond Church at Highland Ave | 1646 Highland Ave, Portsmouth, OH 45662, Usa | | 31-0893504 |
| Cradle Pregnancy Care Center | 1112 Gallia St, Portsmouth, OH 45662, Usa | | 31-1468439 |
| Dorothy Knost Children's Summer Music Workshop | 808 Offnere St, Portsmouth, OH 45662-4231 | | 81-3157732 |
| Family Recovery Services | 104 Erin Ct Hillsboro, Ohio 45133 | | 31-1129448 |
| Fort Hill Christian Youth Camp | 13500 Fort Hill Rd, Hillsboro, OH 45133, Usa | | 31-0804748 |
| Friends of the West Union Library | 157 High St, Peebles, Ohio 45660 | | 34-1627878 |
| Goodwill Industries of Southern Ohio, Inc. (GISO) | 1910 Robinson Avenue, Portsmouth, Ohio 45662 | | 31-0914931 |
| Grown, Inc. | 9116 Hamer Rd, Georgetown, OH 45121, Usa | | 31-0893578 |
| Highland County Historical Society | 151 E Main St, Hillsboro, OH 45133, Usa | | 31-6056566 |
| Highland County Homeless Shelter | 145 Homestead Ave. Hillsboro, Ohio 45133 | | 31-1547454 |
| Highland County Senior Citizens Center | 185 Muntz St, Hillsboro, Ohio 45133 | | 31-0794045 |
| Hospice of Hope | 909 Kenton Station Dr, Maysville, KY 41056, Usa | | 61-1145339 |
| Humane Society of Adams County | P.o. Box 245 11481 St Rt 41 West Union, OH 45693 | | 86-1175774 |
| Humane Society of Buffalo Trace | | | 20-4230157 |
| Kamp Dovetail | 9800 N Shore Dr, Hillsboro, OH 45133, Usa | | 31-1102457 |
| Limestone Family YMCA | 1080 Us 68, Maysville, KY 41056 | | 61-1080836 |
| Maysville Players | 116 West 2nd Street, Maysville, KY 41056 | | 61-6035038 |
| MDH Heartstrings Filthy 5K | Ford Acres Farm In Maysville, Kentucky | | 47-4576562 |
| Mt. Hope Bible Camp | 3162 Mt Hope Rd, Otway, OH 45657, Usa | | 23-7297226 |
| National Underground Railroad Museum | 38 W 4th St, Maysville, KY 41056 | | 61-1290697 |
| On Our Way Home Inc. | 1244 Eifel Cove, Fayetteville, OH 45118, Usa | | 84-3569606 |
| OSU Extension Scioto County | Scioto County Courthouse, 602 7th St, Portsmouth, OH 45662, Usa | | 31-1262987 |
| Pike Heritage Museum | 110 South Market Street, Waverly, Ohio 45690 | | 31-1075237 |
| Pioneer Village of Wheelersburg Ohio | 50 Shela Blvd, Wheelersburg, OH 45694-8972 | | 61-1801880 |
| Scioto County Special Olympics | 2619 Gallia St, Portsmouth, OH 45662-4805 | | 31-1291410 |
| Scioto Hills Christian Camp & Retreat Center | 1009 Martin Rd, Wheelersburg, OH 45694, Usa | | 31-0805764 |
| Shawnee Nature Club | Portsmouth, OH 45662-0766 | | 20-8705392 |
| Sojourner House | 1702 Highland Ave, Portsmouth, OH 45662-3611 | | 27-1675281 |
| Southern Ohio Medical Center (SOMC) | 1805 27th St, Portsmouth, OH 45662, Usa | | 31-6050653 |
| St. Francis Catholic Outreach Center | 2311 Stockham Ln, Portsmouth, OH 45662, Usa | | 81-3847823 |
| St. Vincent de Paul Society | 426 E Main St, West Union Oh 45693 | | 80-0383858 |
| The Arc of Appalachia | 7660 Cave Rd, Bainbridge, OH 45612, Usa | | 31-1434730 |
| The Counseling Center | 411 Court St, Portsmouth, OH 45662, Usa | | 31-1070665 |
| Tom Browning Boys and Girls Club | 241 E Maple Leaf Rd, Maysville, KY 41056, Usa | | 61-0474747 |
| Venture Productions | 11516 State Rte 41, West Union, OH 45693, Usa | | 31-0985946 |
| Victory Christian Center | 719 Us-62, Maysville, KY 41056, Usa | | 25-7419943 |
| Wild Horse Rescue | 714 Diehlman Rd Mc Dermott, OH 45652 | | 26-2453468 |
| Wings of Hope Recovery Services, Inc. | 2nd Ward, Portsmouth, OH 45662 | | 82-3426089 |
